Monday, May 17, 2021

The top 10 signs you've been poisoned with strychnine

Sir Charles Bell, 1809, Public domain

While poking around the internet for strychnine I came across this excellent (?) list of the 10 main symptoms of strychnine poisoning from the University of Bristol's School of Chemistry:

  1. Initial symptoms are tightness and twitching of the muscles, agitation, and hyperreflexia. 
  2. Stiffness of the body. 
  3. Lockjaw. 
  4. Frothing of the mouth. 
  5. Cessation of respiration. 
  6. Tetanus-like attacks appear every 10-15 minutes. During these attacks the eyeballs protrude and the pupils enlarge. 
  7. Severe cyanosis, which disappears after the attack subsides. 
  8. The attacks (each lasting about 3-4 minutes) appear to be spontaneous while other times they are the result of external stimuli, i.e. noises, slight movements, or flashes of light. The patient never loses consciousness. 
  9. When the poisoning is left untreated each attack lasts longer than the previous and the interval between them grows shorter. 
  10. Up to 10 attacks occur before death or recovery. This could happen from 10 minutes to 3 hours and is a result of asphyxiation or inner tissue paralysis.
Sounds pleasant. Not.

My reading has informed me that someone with a full stomach, such as Uncle Charley after eating dinner at his fraternity, takes longer to die. Charley took more than two or three hours to die, while David Puskin only took 20-30 minutes since he had just woken up.

Since noise or flashes of light can also trigger the spasms, I can only imagine what a panicked fraternity house on a Saturday night sounded like and what that did to Charley's state.

-30-

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